Thursday, January 3, 2008

Wilms' Tumor Staging

Stage I(~40% of patients)
Stage I WT is defined as tumor limited to the kidney and completely removed by surgery.The tumor is not ruptured at any time during the surgery.The blood vessels around the kidney are not involved with tumor.There is no remaining cancer visible beyond the area where the surgeon operates.

Stage II (~25% of patients)
Stage II WT is when tumor extends beyond the kidney but is completely removed by surgery.The extension beyond the kidney can be due to blood vessel involvement, local tumor "spillage" during surgical removal, or other nearby tumor extension.There is no remaining cancer is visible at or beyond the area where the surgeon operated.

Stage III (~25% of patients)
Stage III WT is when all of the visible tumor can not be completely removed with surgery, and there is tumor left behind but only in the abdomen.

Stage IV (~10% of patients)
Stage IV WT is defined as disease that has spread outside of the abdomen via the blood, aka hematogenous metastases.The areas in the body where WT can spread include the lung, liver, bone, brain, or to a combination of these sites.

Stage V (5% of patients )
St age V WT is the presence of bilateral renal involvement at initial diagnosis.